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SCID Mouse Model Expressing Human HLA-A2.1

Description:

Reagent Description
NOD.CB17-PrkdcSCID (SCID mouse) was crossed once with NOD.B6-TgN(HLA-A2.1)1Enge/Dvs, and the doubly heterozygous offspring were backcrossed once to NOD.CB17-PrkdcSCID, to make the strain homozygous for Prkdc SCID, then sibling-mated to fix the strain homozygous for TgN(HLA-A2.1)1Enge.
 
A full description can be found at the Jackson Laboratory, where this strain is sold as stock number 004262. Use of this strain by companies or for-profit entities requires a license from the U.Va. Patent Foundation.

Strain Name
NOD.Cg-PrkdcscidTg (HLA-A2.1)1Enge/Dvs

References
Clin Immunol. 2004 Sep;112(3):273-83. (Available online.)

Patent Information:
Category(s):
Mouse Strains
For Information, Contact:
Stephanie Miller
Licensing Associate
UVA
stephanie@uvapf.org
Inventors:
Victor Engelhard
Keywords:
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