Description:
Reagent Description
NOD.CB17-PrkdcSCID (SCID mouse) was crossed once with NOD.B6-TgN(HLA-A2.1)1Enge/Dvs, and the doubly heterozygous offspring were backcrossed once to NOD.CB17-PrkdcSCID, to make the strain homozygous for Prkdc SCID, then sibling-mated to fix the strain homozygous for TgN(HLA-A2.1)1Enge.
A full description can be found at the Jackson Laboratory, where this strain is sold as stock number 004262. Use of this strain by companies or for-profit entities requires a license from the U.Va. Patent Foundation.
Strain Name
NOD.Cg-PrkdcscidTg (HLA-A2.1)1Enge/Dvs
References
Clin Immunol. 2004 Sep;112(3):273-83. (Available online.)