Latest technologies from UVAhttp://uva.technologypublisher.comBe the first to know about the latest inventions and technologies available from UVAen-USMon, 24 Jul 2017 19:26:59 GMTWed, 06 Feb 2013 10:54:44 GMThttp://blogs.law.harvard.edu/tech/rssestabrook@virginia.eduCopyright 2017, UVANovel Dye Improves Breast Cancer Imaging, Detectionhttp://uva.technologypublisher.com/technology/11835Wed, 06 Feb 2013 10:54:44 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/11835Human C3 (Complement Protein) Antibodieshttp://uva.technologypublisher.com/technology/9083Production and Reactivity These mouse IgG1 monoclonal antibodies were generated against human C3 and recognize mouse and human homologs of C3 and its breakdown products C3b and iC3b.Clone Numbers10C76C9-D2-A6ApplicationsFC, ELISAReferencesMol Immunol. 2007 Jan;44(4):377-88.Wed, 07 Mar 2012 09:34:24 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9083Dynein Light Chain 1/3 (DYNLT1/3) Antibodieshttp://uva.technologypublisher.com/technology/9082Production and Reactivity These mouse IgG1 monoclonal antibodies recognize rat and human homologs of both Dynein Light Chain 1 (DYNLT1) and Dynein Light Chain 3 (DNYLT3).Clone Numbers10F6-D1-D96C4-C12-F8ApplicationsIP, IFReferencesJ Biol Chem. 2007 Dec 21;282(51):36871-8.Wed, 07 Mar 2012 09:34:23 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9082Nuclear Transport Factor 2 (NTF2) Antibodieshttp://uva.technologypublisher.com/technology/9081Wed, 07 Mar 2012 09:34:22 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9081Multiplex PCR Detection of Viral, Parasite and Bacterial Pathogenshttp://uva.technologypublisher.com/technology/9080Wed, 07 Mar 2012 09:34:20 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9080SMARCAL1 (ATPase A) Antibodieshttp://uva.technologypublisher.com/technology/9079Wed, 07 Mar 2012 09:34:18 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9079Bordetella Pertussis Adenylate Cyclase (AC) Toxin Antibodyhttp://uva.technologypublisher.com/technology/9078Wed, 07 Mar 2012 09:34:16 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9078Method for Efficient Mass-Production of Surface Textureshttp://uva.technologypublisher.com/technology/9076 Courtesy of Gupta laboratory Microscopic view of a laser micro-textured surface. BackgroundSurface texturing has become an important tool for enhancing surface properties, particularly in fields such as solar and wind energy, aeronautics and medicine. Surface texture is typically generated by chemical etching, a costly and time-consuming process that is known not to be very effective for polycrystalline and thin film semiconductors. Invention DescriptionResearchers at the University of Virginia have developed novel methods for generating micro- and nano-texture...Wed, 07 Mar 2012 09:34:12 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9076MBP/Beta-Tubulin Fusion Proteinshttp://uva.technologypublisher.com/technology/9075DescriptionThe isotype-defining domain (C-terminal 16 amino acids) of each class of human beta-tubulin was fused to Maltose Binding Protein (MBP) and expressed in bacteria. The fusion proteins* are expressed in high amounts, can be purified by maltose chromatography and are very soluble in aqueous buffers. The proteins can be used as a standard in quantitative western blotting, dot blotting and ELISA.ReferencesMethods Cell Biol. 2010;95:33-46. (Available online.) *The fusion proteins are expressed from a modified pMal-C2 vector. Commercial use of the fusion proteins may require a license from ...Wed, 07 Mar 2012 09:34:10 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9075Nidogen/Enactin Antibodieshttp://uva.technologypublisher.com/technology/9074Wed, 07 Mar 2012 09:34:08 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9074Human HLA-Expressing Mouse Strainshttp://uva.technologypublisher.com/technology/9073Reagent DescriptionsTwo reagents are available: HLA-A2.1: This transgenic mouse strain was constructed by microinjection of the 7kb EcoRI fragment containing the full-length HLA-A2.1 gene into fertilized eggs from C57BL/6 mice. The strain expresses human class I MHC Ag HLA-A2.1 on cells from the spleen, bone marrow and thymus. A full description can be found at the Jackson Laboratory, where this strain is sold as stock number 003475. Use of this strain by companies or for-profit entities requires a license from the U.Va. Patent Foundation. HLA-AAD: This strain was constructed by microinject...Wed, 07 Mar 2012 09:34:08 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9073TASK1 and TASK3 Knockout Mouse Strainshttp://uva.technologypublisher.com/technology/9072Reagent DescriptionsFive reagents are available: Task1flox: In this strain, the gene for TASK-1 (K2P3.1, Kcnk3) has been flanked by loxP sites in order to support Cre-mediated excision. Targeting constructs were generated from restriction fragments of genomic DNA surrounding exon II of each TASK-1 derived from a BAC construct. Flanking loxP sites and a neomycin resistance cassette were inserted into the gene fragments, and the resulting construct was transfected into embryonic stem cells for homologous recombination. Chimeric founders were obtained following blastocyst injection with ES cells...Wed, 07 Mar 2012 09:34:07 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9072Multimodality Imaging Probe for Protein Critical to the Development of Arterial Obstructions, LOX-1http://uva.technologypublisher.com/technology/9069Executive SummaryThe invention is a multimodality imaging probe for detecting the oxidized LDL receptor, LOX-1. The researchers have successfully demonstrated LOX-1 staining using SPECT/CT, MRI and fluorescent imaging.BackgroundLOX-1 is a type II membrane protein with a short N-terminal cytoplasmic domain and a long C-terminal extracellular domain that is the receptor for oxidized LDL. It is expressed in endothelial cells, proliferated smooth muscle cells and macrophages. It has been shown that LOX-1 plays a critical role in atherogenesis, the development of plaques within arteries. These plaq...Wed, 07 Mar 2012 09:34:04 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9069Novel Atherosclerotic Plaque Detection/Assessment Technique for the Treatment of Heart Diseasehttp://uva.technologypublisher.com/technology/9068 Courtesy Meyer Laboratory SPECT/CT imaging (A), phosphor imaging (B) and Sudan IV staining (C). All mice injected with LOX-1 probe had hotspots in the aortic arch (sagittal, coronal and transversal plane). Executive SummaryUniversity of Virginia researchers have developed a novel, non-invasive imaging technique for the detection and assessment of atherosclerotic plaques. This technique detects atherosclerotic lesions and can identify which are rupture-prone, vulnerable plaques, leading to an accurate assessment of heart disease a...Wed, 07 Mar 2012 09:34:04 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9068Novel Compounds for the Treatment of Diarrheal Diseaseshttp://uva.technologypublisher.com/technology/9067Wed, 07 Mar 2012 09:34:03 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9067Novel Compounds for Prevention and Treatment of Bacterial Infections and Biofilmshttp://uva.technologypublisher.com/technology/9066Executive SummaryUniversity of Virginia researchers have created novel derivative compounds of FDA-approved drug Nitazoxanide (NTZ) that show reduced toxicity, improved bioavailability and greater efficacy against bacterial infections and biofilms.BackgroundOpportunistic hospital-acquired pathogens, including S. epidermidis and S. aureus, are the leading cause of catheter and in-dwelling device-associated infections. Their ability to cause disease depends on adherence to polymer surfaces, where they form biofilms. These infections lead to increased morbidity, mortality, lengths of hospitalizat...Wed, 07 Mar 2012 09:34:02 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9066Method and Device for Maximizing Memory System Bandwidth by Accessing Data in a Dynamically Determined Orderhttp://uva.technologypublisher.com/technology/9065Wed, 07 Mar 2012 09:34:01 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9065FLUX SHUTTLE RAM: High-Density Magnetic Random Access Memoryhttp://uva.technologypublisher.com/technology/9064Executive SummaryThe invention is a novel method for achieving magnetic random access memory (MRAM) that enables higher memory densities and faster write speeds while lowering the energy consumed when writing to memory.BackgroundAlthough non-volatile computer memory has the ability to store information even when not powered, it is typically disadvantaged by cost or performance when compared to volatile types of memory. MRAM, a type of non-volatile memory, is expected to overcome these disadvantages and potentially displace volatile memory technologies, enabling more energy-efficient computers ...Wed, 07 Mar 2012 09:34:00 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9064MAP Kinase 2 Antibodyhttp://uva.technologypublisher.com/technology/9062Production and Reactivity This mouse IgG2a monoclonal antibody was generated against HPLC purified murine recombinant MAP kinase and recognizes avian, human, mouse and rat homologs.Clone Number1B9-B9-E4ApplicationsWB, IPWed, 07 Mar 2012 09:33:58 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9062Integrative Technique for Improved Signal-to-Noise Ratio in Medical Imaginghttp://uva.technologypublisher.com/technology/9061Wed, 07 Mar 2012 09:33:58 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9061A Novel Spline-Based Algorithm for Multidimensional Displacement and Strain Estimationhttp://uva.technologypublisher.com/technology/9059Researchers at the University of Virginia have developed a novel motion estimation algorithm based on a continuous representation of discrete-sample images, with accuracy better than one 100th of a sample. A novel strategy is employed to reduce computational cost and minimize memory requirements. In addition to rigid body motion, local stretching/compression and shear, or other complex deformations, can be quantified.Motion estimation is critical to many modern signal-processing algorithms. In medical imaging, for example, motion estimation is used to align images in extended field of view app...Wed, 07 Mar 2012 09:33:56 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9059Self-Integrated Sandwich Panel Design for Improved Strength, Reduced Failure Ratehttp://uva.technologypublisher.com/technology/9058Wed, 07 Mar 2012 09:33:55 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9058Novel Technique for More Efficient Vapor Depositionhttp://uva.technologypublisher.com/technology/9057Executive SummaryThe invention involves a novel process and apparatus that use hollow cathode technology to improve any evaporation-based method for coating the surface of materials.BackgroundVapor deposition is a process for applying any form of coating to a material substrate. Although existing techniques are somewhat effective at performing vapor deposition, they typically face significant drawbacks. For instance, high flow rates of gas delivery are required, necessitating high-capacity pumps. In addition, with existing methods, the cathode-delivered gas jet is directed into the path of the...Wed, 07 Mar 2012 09:33:54 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9057Use of Monoclonal Antibodies to Target Cancer Cellshttp://uva.technologypublisher.com/technology/9054The use of monoclonal antibodies in cancer diagnosis and treatment, while promising, is also problematic. Current cancer therapies that rely on this technology require the identification of specific epitopes that are expressed at high levels for a given form of cancer but are expressed at low levels on normal tissues and the development of monoclonal antibodies specific for those epitopes that show minimal cross-reactivity with normal tissues. While most studies have worked to identify epitopes and their corresponding antibodies in order to diagnose and treat specific forms of cancer, research...Wed, 07 Mar 2012 09:33:52 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9054Inverted Well Plate for Large-Scale Cell Culturehttp://uva.technologypublisher.com/technology/9052Wed, 07 Mar 2012 09:33:50 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9052Human Mast Cell Line Ideal for Inflammation Studieshttp://uva.technologypublisher.com/technology/9051Wed, 07 Mar 2012 09:33:49 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9051Phospho-Y694/699 STAT5A/B Antibodyhttp://uva.technologypublisher.com/technology/9050 Normal 0 false false false MicrosoftInternetExplorer4 Production and Reactivity This chicken antibody was generated against a phospho-peptide of amino acids 690/4-701/6 of human STAT5A/B and recognizes only phosphorylated STAT5A/B.ApplicationsWB, IFReferencesMol Endocrinol. 2008 Aug;22(8):1781-96. (Available online.)Wed, 07 Mar 2012 09:33:48 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9050Super-Rich Hydrogen Storage Nanomaterials with Intermediate Bond Strengthhttp://uva.technologypublisher.com/technology/9049The quest for vehicles powered by alternative sources of fuel such as hydrogen has led to an explosion of research into new materials for storing and releasing hydrogen. Currently, one of the main challenges in the large scale development of hydrogen as a fuel is that a convenient and economical storage system does not exist. Hydrogen storage technologies face a number of key challenges: 1) they must be able to store enough hydrogen for a vehicle to have a reasonable driving range; 2) they must be sufficiently light and compact so as not to change the efficiency of the vehicle; and 3) they mus...Wed, 07 Mar 2012 09:33:47 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9049E. coli LacI Antibodyhttp://uva.technologypublisher.com/technology/9048Production and Reactivity This mouse IgG1 monoclonal antibody was generated against E. coli LacI and recognizes recombinant proteins containing the LacI tag.Clone Number9A5ApplicationsWB, IF, IHCReferencesGenes Dev. 2001 Jun 15;15(12):1506-17. (Available online.)Wed, 07 Mar 2012 09:33:46 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9048Zizimin1 (CDC42 GEF) Antibodyhttp://uva.technologypublisher.com/technology/9047Production and Reactivity This mouse IgG2a monoclonal antibody was generated against human zizimin1 and recognizes amino acids 1184-1215 of human and primate homologs.Clone Number8B3-C3-E4ApplicationsWB, IP, IFWed, 07 Mar 2012 09:33:45 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9047RhoG Antibodyhttp://uva.technologypublisher.com/technology/9046Wed, 07 Mar 2012 09:33:44 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9046High Sensitivity Infrared Sensing Apparatushttp://uva.technologypublisher.com/technology/9045Researchers at the University of Virginia have developed a novel idea for IR sensor system design where the detector is suspended away from electrical and thermal connections. Sensitivity of such a system is expected to be an order of magnitude better than the current IR sensors.Infrared sensors have become widely used in many detection systems, most notably for night vision applications. The sensitivity of an infrared sensor is limited, however, by thermal losses in the detector itself. Typically, an infrared sensor consists of a suspended platform coated with material sensitive to infrared r...Wed, 07 Mar 2012 09:33:44 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9045An Improved Method for Diagnosing Seizureshttp://uva.technologypublisher.com/technology/9044Executive SummaryThe invention is a novel patient-monitoring device that uses limb accelerometry to more accurately diagnose epileptic seizures (ES).BackgroundNearly 10 percent of Americans will experience at least one seizure during their lifetime. Unfortunately, however, seizures can be difficult to diagnose using existing technology and methods, which often face many practical challenges. For example, clinical observation of convulsive movements is subjective and often unreliable. Tools such as electroencephalography (EEG) and continuous video-EEG (CV-EEG) are cumbersome and have a variety ...Wed, 07 Mar 2012 09:33:42 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9044Lightweight Structures for Improving Performance of Aerospace Componentshttp://uva.technologypublisher.com/technology/9043Invention DescriptionAerospace vehicles have many components that are subjected to high thermal and mechanical loading. In addition to heat and strength considerations, these components must be extremely lightweight in order to reduce associated fuel costs. The invention utilizes heat pipe concepts to improve heat transfer throughout cellular core panel structures. Specifically, these structures are well adapted to dissipate heat and withstand large static and dynamic forces, making them well suited for aerospace applications. A published Patent Cooperation Treaty (PCT) application covering th...Wed, 07 Mar 2012 09:33:42 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9043Amorphous Steel Composites and Methods for Their Manufacturehttp://uva.technologypublisher.com/technology/9041Amorphous steels exhibit superb mechanical properties for a variety of high-performance applications, but they are significantly more brittle than conventional high-carbon steels. The fracture toughness of this group of materials must be improved prior to utilizing them as structural components. Scientists at the University of Virginia have developed an amorphous steel composite that exhibits enhanced fracture strengths and elastic moduli, as well as fracture features that indicate improved ductility. They have also developed practical methodologies to successfully produce these composites. In...Wed, 07 Mar 2012 09:33:40 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9041Cytoplasmic Dynein Intermediate Chain Antibody (Clone 74.1)http://uva.technologypublisher.com/technology/9040Wed, 07 Mar 2012 09:33:39 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9040Dynein Light Chain 1 (DYNLT1) Antibodyhttp://uva.technologypublisher.com/technology/9039Production and Reactivity This mouse IgG1 monoclonal antibody was generated against human Dynein Light Chain 1 (DYNLT1) and recognizes rat and human homologs.Clone Number7A9-F4-H10ApplicationsWB, IFReferencesJ Biol Chem. 2007 Dec 21;282(51):36871-8.Wed, 07 Mar 2012 09:33:38 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9039Dynein Light Chain 3 (DYNLT3) Antibodyhttp://uva.technologypublisher.com/technology/9038Production and Reactivity This mouse IgG2a monoclonal antibody was generated against rat Dynein Light Chain 3 (DYNLT3) and recognizes rat and human homologs.Clone Number10A3-C8-A1ApplicationsWB, IFReferencesJ Biol Chem. 2007 Dec 21;282(51):36871-8.Wed, 07 Mar 2012 09:33:38 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9038Sno Knockout Mouse Strainhttp://uva.technologypublisher.com/technology/9037Reagent DescriptionThese mutant mice may be useful in studies of T cell activation, T cell receptor stimulation and TGF-beta signaling. A targeting vector was designed to replace exon 1 of the endogenous gene with a lacZ gene (with a nuclear localization signal) and a loxP-flanked PGK-neo cassette. This construct was microinjected into (129X1/SvJ x 129S1/Sv)F1-derived R1 embryonic stem (ES) cells. Correctly targeted ES cells were injected into C57BL/6 blastocysts, which were then implanted into pseudopregnant foster mothers, resulting in heterozygous offspring. These mice were then backcrossed...Wed, 07 Mar 2012 09:33:37 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9037Androgen Receptor Antibody (AR21)http://uva.technologypublisher.com/technology/9035Production and Reactivity This rabbit polyclonal antibody was generated against the N-terminal 21 amino acids of human androgen receptor (AR).ApplicationsWB, IP, IFReferencesMol Cell Biol. 2007 May;27(9):3390-404. (Available online.)Wed, 07 Mar 2012 09:33:35 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9035p120/Catenin Antibody (Clone 2B12)http://uva.technologypublisher.com/technology/9034Production and Reactivity This mouse IgG1 antibody was generated against tyrosine phosphoproteins purified from chicken embryonic fibroblasts (CEFs) expressing pp60/c-src 527F and 2A/527F. It recognizes mouse, rat, hamster, human and chicken homologs of p120/catenin.Clone Number2B12ApplicationsWB, IPReferencesProc Natl Acad Sci U S A. 1990 May;87(9):3328-32. (Available online.) Mol Cell Biol. 1991 Feb;11(2):713-20. (Available online.)Wed, 07 Mar 2012 09:33:35 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9034Phospho-Tyrosine Antibodyhttp://uva.technologypublisher.com/technology/9033Production and Reactivity This mouse IgG2a antibody was generated against tyrosine phospho-proteins purified from chicken embryonic fibroblasts (CEFs) expressing pp60/c-src 527F and 2A/527F and recognizes tyrosine phospho-proteins in mouse, rat, hamster, human and chicken cell lines.Clone Number6G9ApplicationsWB, IPReferencesProc Natl Acad Sci U S A. 1990 May;87(9):3328-32. (Available online.)Wed, 07 Mar 2012 09:33:34 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9033Neutrophil-Specific, NIR Fluorescent Imaging Agenthttp://uva.technologypublisher.com/technology/9032 Courtesy of Pan, Zhang, Xiao This figure shows NIR fluorescence image three hours after injection of cFLFLF-PEG76-Cy7 in a mouse model of ear inflammation. (A) shows probe accumulation in the PMA-treated ear. (B) shows probe specificity shown by pre-injection with a non-fluorescence peptide. Reagent Description This reagent is a Cy7-conjugated, PEG-modified hexapeptide that specifically binds the formyl peptide receptor (FPR) of neutrophils. After tail vein injection of the agent, sites of inflammation, where neutrophils ...Wed, 07 Mar 2012 09:33:33 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9032GnRH Neuron GFP-Expressing Mouse Strainhttp://uva.technologypublisher.com/technology/9028Wed, 07 Mar 2012 09:33:30 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9028Circadian Rhythm-Induced Luciferase Expression in a Rat Strainhttp://uva.technologypublisher.com/technology/9027Reagent DescriptionThis rat strain is useful for studying the organization of the mammalian circadian system. In this transgenic rat line, luciferase is rhythmically expressed under the control of the mouse Per1 promoter. Cells isolated from the suprachiasmatic nuclei (SCN) continue rhythmical light emission for up to 32 days in vitro. A mouse Per1 genomic fragment of 6.7 kb was ligated directly to the second codon of the firefly luciferase cDNA flanked by the SV40 late polyadenylation signal. The mPer1 fragment includes five functional E box regions, a transcription initiation site, the first...Wed, 07 Mar 2012 09:33:29 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9027Crohn's Disease Mouse Modelhttp://uva.technologypublisher.com/technology/9026Wed, 07 Mar 2012 09:33:29 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9026Diabetes-Resistant Mouse Strainshttp://uva.technologypublisher.com/technology/9025Wed, 07 Mar 2012 09:33:28 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9025SIMPLE: A Novel Immunohistochemical Method for Multiple Antigen Labelinghttp://uva.technologypublisher.com/technology/9024Executive Summary A new method for immunohistochemical (IHC) staining allowing colocalization studies of six or more proteins within a single tissue section.Background Visual colocalization of molecular species within sectioned tissue can provide powerful insights into cellular biochemistry and often provides the basis for further study of protein-protein interactions. However, current methods are imperfect and are limited to at most three simultaneous probes. Multi-color fluorescence is limited by few non-overlapping combinations of fluorescent tags, antibody cross-reactivity, photobleachi...Wed, 07 Mar 2012 09:33:27 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9024Sept6 Antibodyhttp://uva.technologypublisher.com/technology/9023Production and Reactivity This mouse monoclonal antibody was generated against a tetramer of GST-BD3/Sept2/Sept6/Sept7 and recognizes human and canine homologs of Sept6.Clone number9E7ApplicationsWB, IPReferencesMol Biol Cell. 2005 Oct;16(10):4648-59.Wed, 07 Mar 2012 09:33:26 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9023Novel Targets in Treating Erectile Dysfunctionhttp://uva.technologypublisher.com/technology/9022 Courtesy Lysiak, Palmer, Kavoussi Figure 1. Heterozygote and knockout mice are unable to maintain erections. When the cavernous nerve is stimulated, wild type mice (blue) are able to maintain high intracavernous pressures (ICPs) for approximately five minutes, whereas both heterozygote (green) and knockout (red) mice are only able to initiate a blunted ICP response without the ability to sustain an erection. Erectile dysfunction (ED) is a major health problem affecting approximately 30 million men in the Uni...Wed, 07 Mar 2012 09:33:25 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9022Adenosine Receptor-Expressing HEK293 and CHO-K1 Cell Lineshttp://uva.technologypublisher.com/technology/9021DescriptionThese HEK293 and CHO-K1 cells stably express all four types of human adenosine receptors. Membranes prepared from these cells can be used to screen compounds to determine their affinities for human adenosine receptors. U.S. patent 5,854,081 has been issued on this technology.ReferencesBiochem Pharmacol. 1996 Feb 23;51(4):545-55. (Available online.)Wed, 07 Mar 2012 09:33:25 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9021Ga i-2 Antibody (Clone 5C11)http://uva.technologypublisher.com/technology/9020Wed, 07 Mar 2012 09:33:24 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9020Adenosine Receptor A2A Antibody (Clone 7F6)http://uva.technologypublisher.com/technology/9019Wed, 07 Mar 2012 09:33:23 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9019Novel Hip Rehabilitation Device for Improved Range of Motionhttp://uva.technologypublisher.com/technology/9018Executive SummaryThis invention is a novel device that provides continuous passive motion physiotherapy to patients following hip surgery or replacement procedures. The novel design incorporates both flexion and extension of the hip joint, providing the complete range of motion necessary for rehabilitation. BackgroundContinuous passive motion (CPM) physiotherapy helps patients regain their natural range of motion and also improves patient comfort following joint surgery or injury. Although effective devices exist for knee and shoulder CPM, no device currently exists for effective hip CPM. Whil...Wed, 07 Mar 2012 09:33:22 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9018BM180 (Basement Membrane Protein, 180kDa) Antibodyhttp://uva.technologypublisher.com/technology/9017Wed, 07 Mar 2012 09:33:21 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9017Improving the Accuracy of Continuous Glucose Sensors for Type 1 and Type 2 Diabeteshttp://uva.technologypublisher.com/technology/9014BackgroundContinuous glucose sensors (CGSs) offer the potential to markedly change our understanding of glucose homeostasis in health and disease and to provide the missing information required to achieve near-normoglycemia among persons with both Type 1 and Type 2 diabetes. Despite their having appeared on the scene less than five years ago, CGSs already have been shown to be associated with short-term reductions in glucose variability, time spent in nocturnal hypoglycemia, time spent in hyperglycemia and lower glycosylated hemoglobin values. Their potential to assist patients and their famil...Wed, 07 Mar 2012 09:33:17 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9014Method, System and Computer Program Product for the Detection of Physical Activity by Changes in Heart Rate, Assessment of Fast-Changing Metabolic States and Applications of Closed and Open Control Loop in Diabeteshttp://uva.technologypublisher.com/technology/9013Wed, 07 Mar 2012 09:33:15 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9013Method and System for Capillary Force Actuatorshttp://uva.technologypublisher.com/technology/9012For micro-electromechanical systems (MEMS) and bio-MEMS (e.g., micro total analysis systems, or MTAS), a variety of force actuation methods have been used to either move structures or to induce stress in stationary structures, including electromagnetic, electrostatic, pneumatic, thermal, piezoelectric, magnetostrictive, among others. Each of these actuation technologies has advantages, disadvantages and trade-offs in terms of performance metrics such as force capability, total displacement, actuation bandwidth, ease of integration to particular applications, and manufacturability. Electrostati...Wed, 07 Mar 2012 09:33:13 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9012NORE1A Antibodieshttp://uva.technologypublisher.com/technology/9010Wed, 07 Mar 2012 09:33:12 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9010GABA-A Receptor Gamma2 Subunit Antibodyhttp://uva.technologypublisher.com/technology/9009Wed, 07 Mar 2012 09:33:11 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9009NOS (Nitric Oxide Synthase) Antibody (Clone 3F7)http://uva.technologypublisher.com/technology/9008Wed, 07 Mar 2012 09:33:10 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9008Adaptive Brain Stimulation Technique for Next-Generation Neuromodulation Therapyhttp://uva.technologypublisher.com/technology/9005Wed, 07 Mar 2012 09:33:05 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9005New Platform for Targeted Intravascular Drug and Gene Deliveryhttp://uva.technologypublisher.com/technology/9004Executive SummaryThis novel device combines the imaging capabilities of intravascular ultrasound (IVUS) with the therapeutic effectiveness of targeted microbubbles. The result is a new paradigm for targeted drug and gene delivery that yields safer and more effective treatments. This device also enables treatment of diseases for which therapy is currently limited and not effective, such as peripheral artery disease.BackgroundTraditional or systemic treatment of diseases requires dosing patients in excess of the minimum therapeutically effective dose, which can lead to unnecessary off-target eff...Wed, 07 Mar 2012 09:33:03 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9004Novel Treatment for Improved Heart Function Following Heart Attackhttp://uva.technologypublisher.com/technology/9003Executive SummaryUniversity of Virginia researchers have developed a novel treatment that dramatically improves heart function after a heart attack by modifying the mechanical characteristics of the affected region (the infarct).BackgroundOnce the myocardium dies during a heart attack, it is gradually replaced over the course of several weeks by scar tissue, accompanied by loss of pumping effectiveness, dilation of the left ventricle and eventual heart failure. Current therapies aim to limit damage during the first few hours by reopening coronary arteries and then slow remodeling and progressi...Wed, 07 Mar 2012 09:33:01 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9003Scientific Chart Depicts the Stages of Normal Hematopoiesis in Actual Human Blood Cellshttp://uva.technologypublisher.com/technology/9002The maturation of hematopoietic cells in human bone marrow is essential to the understanding of the process of hematopoiesis for physicians, pathologists, medical students, laboratory technologists, teachers and researchers. Yet to date, no single chart or reference guide exists that depicts all of the stages as shown in photographed human blood cells. Scientists from the University of Virginia led by Charles E. Hess, M.D., have created and assembled an extensive image database of unique benign and malignant diseases and disorders within human blood and bone marrow. From this comprehensive dat...Wed, 07 Mar 2012 09:33:00 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9002Semen Collection and Storage Devicehttp://uva.technologypublisher.com/technology/9001Executive SummaryThis technology is a semen collection device that is better than all other collection devices at recovering ejaculated semen completely, preventing the loss of initial sperm-rich epididymal fractions.BackgroundSemen analysis is the major step to determine fertility of male patients and sperm donors. It requires clinical analysis by a trained medical professional under a microscope, or, increasingly, testing at home with other methods which requires high concentrations of sperm. Freshly ejaculated semen is a complex mixture where the sperm is concentrated in fluid from the epid...Wed, 07 Mar 2012 09:32:59 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/9001CD52 Antibodyhttp://uva.technologypublisher.com/technology/8999Production and Reactivity This mouse IgG1 monoclonal antibody generated against human spermatozoa and recognizes a carbohydrate epitope on the spermatozoa glycoform of CD52.Clone NumberS19 (MHS8-A5-A1-D7)ApplicationsWB, IP, IF, IHCReferencesFASEB J. 1999 Aug;13(11):1303-13.Wed, 07 Mar 2012 09:32:56 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8999Synthesis Method for RSK Inhibitor SL0101http://uva.technologypublisher.com/technology/8998 Courtesy of Hecht, Maloney Executive SummaryThe invention involves a practical synthesis of the Rsk2 inhibitor and potential antitumor agent SL0101-1 and analogues.BackgroundRecent studies have demonstrated the role of Rsk in cell survival signaling and promoting cell survival by regulating the expression and activation of pro-survival proteins such as CREB. This combination of promoting cell survival and prevention of apoptosis causes excessive cell survival, leading to diseases such as cancer and autoimmune disorders. It has been found that Rsk2 is over-expressed...Wed, 07 Mar 2012 09:32:55 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8998Improved Process for Enhanced Electromagnetic Interference (EMI) Shieldinghttp://uva.technologypublisher.com/technology/8997Wed, 07 Mar 2012 09:32:54 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8997Device for Extending Laparoscopic Incisions for Safe and Rapid Removal of Gallbladder or other Specimenshttp://uva.technologypublisher.com/technology/8996Wed, 07 Mar 2012 09:32:53 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8996Human Cytokeratin 8 Antibodyhttp://uva.technologypublisher.com/technology/8994Production and ReactivityThis mouse IgG2b antibody has been generated against the C-terminus (amino acids 472-483) of human Cytokeratin 8.Clone Number1E8-C6-B4ApplicationsWB, IP, IFReferencesJ Biol Chem. 1996 Oct 11;271(41):25684-91.Wed, 07 Mar 2012 09:32:51 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8994Accurate Method for Measuring Nitric Oxide in Bloodhttp://uva.technologypublisher.com/technology/8990Executive SummaryResearchers at the University of Virginia have developed a novel method of detecting nitric oxide (NO) levels in heme-containing samples such as blood.BackgroundBlood gas analysis is typically used to determine the amount of oxygen and carbon dioxide carried in the blood. A third blood gas, nitric oxide (NO), is however not currently measured by routine analysis. NO signaling is abnormal in a variety of human diseases, including asthma, cystic fibrosis, sepsis, diabetes, pulmonary hypertension and sickle cell anemia, among others. Measurement of NO levels in the blood can aid ...Wed, 07 Mar 2012 09:32:47 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8990Combined ECG-Echo for Cardiac Diagnosishttp://uva.technologypublisher.com/technology/8988The most common tool for cardiac screening and diagnosis, the electrocardiogram (ECG) is at best an indirect measure of cardiac dimensions. Specific dimensions of interest including chamber volumes, wall thickness and septal thickness can only be indirect assessed by ECG with overall poor predictive value for these measurements. Historically the ECG has achieved widespread clinical application because of its ease of use and relatively low cost, even though it fails to accurately reflect chamber size and wall thickness. The ECG does provide important information on heart rhythm, possible ischem...Wed, 07 Mar 2012 09:32:46 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8988CD40 Antibodyhttp://uva.technologypublisher.com/technology/8987Production and ReactivityThis mouse IgG1 antibody has been generated against human activated tonsillar B cells and recognizes human CD40.Clone Number626ApplicationsWB, IHC, FCReferencesJ Immunol. 1989 Jun 15;142(12):4144-52.Wed, 07 Mar 2012 09:32:45 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8987Bruton's Tyrosine Kinase (BTK) Antibodyhttp://uva.technologypublisher.com/technology/8986Wed, 07 Mar 2012 09:32:44 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8986Mechanochromic Chemical Sensorshttp://uva.technologypublisher.com/technology/8985 Courtesy of Fraser Lab Executive SummaryResearchers at the University of Virginia have developed a family of light-emitting boron dye compounds that are easily tuned and that change appearance with scratching and heating.BackgroundChemical dyes are used for innumerable applications, from biomedical diagnosis to LEDs in television screens. The application of each particular dye is a function of its environmental sensitivity, intensity and wavelength, among other features. Few chemical dyes, however, show useful changes in appearance with mechanical perturbance, suc...Wed, 07 Mar 2012 09:32:43 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8985Dual Fluorescent/Phosphorescent Oxygen Sensorshttp://uva.technologypublisher.com/technology/8984 Courtesy of Fraser Lab Samples exhibiting the tunable wavelength of the boron dyes Executive SummaryResearchers at the University of Virginia have developed a family of light-emitting boron dye compounds that are easily tuned and that emit fluorescence and oxygen-sensitive phosphorescence after illumination. BackgroundChemical dyes are used for innumerable applications, from biomedical diagnosis to LEDs in television screens. The application of each particular dye is a function of its environmental sensitivity, intensity and wavelength, amon...Wed, 07 Mar 2012 09:32:43 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8984MAP1B Antibody (Clone AA9)http://uva.technologypublisher.com/technology/8983Wed, 07 Mar 2012 09:32:42 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8983MAP2 Antibody (Clone AA6)http://uva.technologypublisher.com/technology/8982Wed, 07 Mar 2012 09:32:41 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8982MAP2 Antibody (Clone AA5)http://uva.technologypublisher.com/technology/8981Wed, 07 Mar 2012 09:32:40 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8981B-Tubulin Antibody (Clone AA2)http://uva.technologypublisher.com/technology/8980Wed, 07 Mar 2012 09:32:40 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8980BV-Tubulin Antibody (Clone AA17)http://uva.technologypublisher.com/technology/8979Wed, 07 Mar 2012 09:32:39 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8979BVI-Tubulin Antibody (Clone AA16)http://uva.technologypublisher.com/technology/8978Wed, 07 Mar 2012 09:32:38 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8978a-Tubulin Antibody (Clone AA13)http://uva.technologypublisher.com/technology/8977Wed, 07 Mar 2012 09:32:37 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8977Detyrosinated a-Tubulin Antibody (Clone AA12)http://uva.technologypublisher.com/technology/8976Wed, 07 Mar 2012 09:32:37 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8976BIII Tubulin Antibody (Clone AA10)http://uva.technologypublisher.com/technology/8975Wed, 07 Mar 2012 09:32:36 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8975BII Tubulin Antibody (Clone 7B9)http://uva.technologypublisher.com/technology/8974Wed, 07 Mar 2012 09:32:35 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8974BII Tubulin Antibody (Clone 6B1)http://uva.technologypublisher.com/technology/8973Wed, 07 Mar 2012 09:32:34 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8973BIII Tubulin Antibody (Clone 2G10)http://uva.technologypublisher.com/technology/8972Wed, 07 Mar 2012 09:32:34 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8972SCID Mouse Model Expressing Human HLA-A2.1http://uva.technologypublisher.com/technology/8969Wed, 07 Mar 2012 09:32:31 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8969Type 1 Diabetes Mouse Model Expressing Human HLA-A2.1http://uva.technologypublisher.com/technology/8968Reagent DescriptionThis model is useful for studying the role of MHC class I molecules in Type 1 Diabetes. The transgenic allele HLA-A2.1 from C57BL/6-Tg(HLA-A2.1)1Enge/J (stock# 3088) was backcrossed 10 generations to NOD/Lt prior to making the homozygote. Homozygous mice carrying the (HLA-A2.1)1Enge transgene ubiquitously express significant quantities of the human MHC class I HLA-A2.1 molecules. These HLA-A2.1 molecules mediate beta cell auto-reactive CD8 T cell responses that, when added to those elicited by endogenous murine MHC class I variants, result in a significantly accelerated rate...Wed, 07 Mar 2012 09:32:31 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8968Ubiquitin E2 T (UBE2T) Antibodyhttp://uva.technologypublisher.com/technology/8967Wed, 07 Mar 2012 09:32:30 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8967Human Cdt1 (1-20) Antibodyhttp://uva.technologypublisher.com/technology/8966Wed, 07 Mar 2012 09:32:29 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8966Lin28 Antibodyhttp://uva.technologypublisher.com/technology/8965Production and Reactivity This rabbit polyclonal antibody was generated against human Lin28 and recognizes mouse and human homologs.ApplicationsWBReferencesJ Biol Chem. 2005 Apr 29;280(17):16635-41. (Available online.)Wed, 07 Mar 2012 09:32:29 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8965Human Geminin Antibodyhttp://uva.technologypublisher.com/technology/8964Wed, 07 Mar 2012 09:32:28 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8964Detection Method for Gene Translocation and DNA Fusion Junctionshttp://uva.technologypublisher.com/technology/8963Executive SummaryResearchers at the University of Virginia have developed a method for high-throughput detection of disease-specific genomic rearrangements and have validated this method using chronic myeloid leukemia patient samples. This detection system can be utilized to provide clinical diagnosis, disease monitoring and treatment efficacy information.BackgroundChromosomal translocations, deletions and amplifications play a major role in many cancers. One such translocation is the Philadelphia chromosome, which has been linked to chronic myeloid leukemia (CML). In this case, the translocat...Wed, 07 Mar 2012 09:32:27 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8963Human Cdt1 (238-546) Antibodyhttp://uva.technologypublisher.com/technology/8962Wed, 07 Mar 2012 09:32:26 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8962Connexin 43 (CX43) flox Mouse Strainhttp://uva.technologypublisher.com/technology/8961Reagent DescriptionMice homozygous for this CX43flox conditional allele are viable and fertile, with loxP sites flanking exon 2 of the targeted gene. Presence of the loxP sites has no reported effect on expression of the targeted gene. When bred to mice that express Cre recombinase, the resulting offspring will have exon 2 deleted in the Cre-expressing tissue(s). These CX43flox mutant mice may be useful in generating conditional mutations for studying the role of connexin and gap junctions in various tissues and systems, including the cardiovascular system.A full description can be found at th...Wed, 07 Mar 2012 09:32:25 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8961GST (Glutathione-S-Transferase) Antibodyhttp://uva.technologypublisher.com/technology/8960Wed, 07 Mar 2012 09:32:25 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8960Gas Expanded Lubricantshttp://uva.technologypublisher.com/technology/8959Executive SummaryThis invention provides a method for lubricating bearings during operation in which mixtures of lubricant and high-pressure gas are supplied inside a reinforced casing. The gas serves to control the viscosity and thermal conductivity of the lubricant such that bearing characteristics, such as power loss, can be minimized as loading and speed conditions change.BackgroundWind turbines operate under a wide range of weather conditions that directly influence the temperature and loading on mechanical components. These natural variations have been shown to cause a large number of th...Wed, 07 Mar 2012 09:32:24 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8959RFID Object Localization System That Simultaneously Offers High Accuracy, Speed, Reliabilityhttp://uva.technologypublisher.com/technology/8958Executive SummaryThe invention is an object localization system that leverages radio frequency identification (RFID) technology to provide a new, GPS-like positioning capability that simultaneously delivers high accuracy, speed and reliability not previously seen in RFID technologies. BackgroundRFID technology typically provides object tracking and identification functionality without providing object localization capabilities. Existing RFID-based localization techniques suffer from inherent position-estimate errors due to various factors (e.g., environmental interferences, radio frequency occ...Wed, 07 Mar 2012 09:32:23 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8958Targeted Treatment for the Inv(16) Subtype of Acute Myeloid Leukemiahttp://uva.technologypublisher.com/technology/8957Wed, 07 Mar 2012 09:32:22 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8957Thermally Responsive Composite Hydrogelhttp://uva.technologypublisher.com/technology/8956Executive SummaryThe purpose of the invention is to produce a thermally sensitive hydrogel, which is a liquid at room temperature and solid at physiological temperature. The hydrogel can be injected at an injury site to deliver therapeutic agents. BackgroundThe products used currently in orthopedic surgery for delivery of protein are flimsy, collagen carriers that are little more than wet sponges. They provide little room for personalized medicine and the precise amount of protein delivered is difficult to quantitate. Chitosan thermogels used currently do not allow desirable tissue growth and ...Wed, 07 Mar 2012 09:32:21 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8956Oral General Anesthetics and Metabolically Resistant Anticonvulsantshttp://uva.technologypublisher.com/technology/8955Wed, 07 Mar 2012 09:32:21 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8955VP5 (HSV-1) Antibodyhttp://uva.technologypublisher.com/technology/8954Wed, 07 Mar 2012 09:32:20 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8954p130/CAS Antibodyhttp://uva.technologypublisher.com/technology/8953Wed, 07 Mar 2012 09:32:19 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8953High-Presence, Low-Bandwidth, Apparent 3-D Video-Conferencing With a Single Camerahttp://uva.technologypublisher.com/technology/8952Wed, 07 Mar 2012 09:32:18 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8952Viscoelastic Silicone Rubber Devices and Related Methodshttp://uva.technologypublisher.com/technology/8951Wed, 07 Mar 2012 09:32:17 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8951Human Serum Albumin (HSA) Antibodyhttp://uva.technologypublisher.com/technology/8950Production and Reactivity This mouse IgG1 monoclonal antibody was generated against human serum albumin (HSA), recognizes only HSA and does not react with chimpanzee, bovine, deer, dog, goat, gorilla, horse, orangutan, porcine, rabbit, rat, turkey, hamster, cat, raccoon, antelope, mule deer, elk, guinea pig, mouse or sheep homologs.Clone Number3B8-H3-G1ApplicationsWB, ELISAReferencesHybridoma. 1987 Apr;6(2):183-90.Wed, 07 Mar 2012 09:32:17 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8950K+ Channel and GPCR-Expressing HEK293 Cell Linehttp://uva.technologypublisher.com/technology/8949DescriptionThese HEK293 cells stably express GIRK1, GIRK4, TRH-R1 and 5-HT1A under G418 selection and exhibit G protein-coupled inwardly rectifying K currents. The cell line is useful for the study of GIRK channel regulation.Wed, 07 Mar 2012 09:32:16 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8949K+ Channel-Expressing HEK293 Cell Linehttp://uva.technologypublisher.com/technology/8948DescriptionThese HEK293 cells stably express GIRK1 and GIRK4 under G418 selection and exhibit G protein-coupled inwardly rectifying K currents. The cell line is useful for the study of GIRK channel regulation.ReferencesProc Natl Acad Sci U S A. 2000 Aug 15;97(17):9771-6. (Available online.)Wed, 07 Mar 2012 09:32:15 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8948Self-Sensing Integrated System for Determining the Position of a Shaft in a Magnetic Bearinghttp://uva.technologypublisher.com/technology/8946Magnetic bearings levitate a rotating object (typically a rotor) with a magnetic field and are unstable in open-loop operation. Position feedback control is required to maintain the rotor in a centered position. Typically, a separate position sensor is used to directly measure the rotor's position for use in this feedback loop. Self-sensing magnetic bearings use the bearing's electrical signals to estimate rotor position.There are two primary classes of self-sensing methods: state estimation and inductance (displacement) measurement from switching Pulse Width Modulation (PWM) amplifier wavefor...Wed, 07 Mar 2012 09:32:14 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8946Hybrid 5-Axis Magnetic Bearing Systemhttp://uva.technologypublisher.com/technology/8945BackgroundMagnetic bearings are commonly used in many rotating machines, such as pumps, compressors and turbines. In such machines, a five-axis, active magnetic bearing configuration is frequently employed; this configuration must maintain power to electromagnets for each of the five axes. In this arrangement, one axial active magnetic thrust bearing acts upon a thrust disk that is attached to a rotor in order to control axial rotor vibrations, while two radial active magnetic bearings act upon the rotor in two directions to control radial vibrations. While this configuration is useful, it suf...Wed, 07 Mar 2012 09:32:13 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8945Frizzled Antibodyhttp://uva.technologypublisher.com/technology/8944Wed, 07 Mar 2012 09:32:12 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8944BMI-1/PSC Antibodyhttp://uva.technologypublisher.com/technology/8943Wed, 07 Mar 2012 09:32:11 GMTestabrook@virginia.eduhttp://uva.technologypublisher.com/technology/8943