Search Results - christopher+kramer

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Multimodality Imaging Probe for Protein Critical to the Development of Arterial Obstructions, LOX-1 Executive SummaryThe invention is a multimodality imaging probe for detecting the oxidized LDL receptor, LOX-1. The researchers have successfully demonstrated LOX-1 staining using SPECT/CT, MRI and fluorescent imaging.BackgroundLOX-1 is a type II membrane protein with a short N-terminal cytoplasmic domain and a long C-terminal extracellular domain that... Published: 3/7/2012   |   Inventor(s): Alexander Klibanov, Dayuan Li, Amit Patel, Craig Meyer, George Beller, David Glover, Christopher Kramer Keywords(s):   Category(s): Recombinant Proteins and Peptides

Novel Atherosclerotic Plaque Detection/Assessment Technique for the Treatment of Heart Disease Courtesy Meyer Laboratory SPECT/CT imaging (A), phosphor imaging (B) and Sudan IV staining (C). All mice injected with LOX-1 probe had hotspots in the aortic arch (sagittal, coronal and transversal plane). Executive SummaryUniversity of Virginia researchers have developed a novel, non-invasive imaging technique... Published: 3/8/2012   |   Inventor(s): Alexander Klibanov, Dayuan Li, Amit Patel, Craig Meyer, George Beller, David Glover, Christopher Kramer Keywords(s): Imaging Category(s): Imaging & Radiology