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Search Results - Recombinant+Proteins+and+Peptides

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MBP/Beta-Tubulin Fusion Proteins
DescriptionThe isotype-defining domain (C-terminal 16 amino acids) of each class of human beta-tubulin was fused to Maltose Binding Protein (MBP) and expressed in bacteria. The fusion proteins* are expressed in high amounts, can be purified by maltose chromatography and are very soluble in aqueous buffers. The proteins can be used as a standard in quantitative...
Published: 3/7/2012   |   Inventor(s): Tony Frankfurter, Anthony Spano
Keywords(s):  
Category(s): Recombinant Proteins and Peptides
Multimodality Imaging Probe for Protein Critical to the Development of Arterial Obstructions, LOX-1
Executive SummaryThe invention is a multimodality imaging probe for detecting the oxidized LDL receptor, LOX-1. The researchers have successfully demonstrated LOX-1 staining using SPECT/CT, MRI and fluorescent imaging.BackgroundLOX-1 is a type II membrane protein with a short N-terminal cytoplasmic domain and a long C-terminal extracellular domain that...
Published: 3/7/2012   |   Inventor(s): Alexander Klibanov, Dayuan Li, Amit Patel, Craig Meyer, George Beller, David Glover, Christopher Kramer
Keywords(s):  
Category(s): Recombinant Proteins and Peptides
Neutrophil-Specific, NIR Fluorescent Imaging Agent
Courtesy of Pan, Zhang, Xiao This figure shows NIR fluorescence image three hours after injection of cFLFLF-PEG76-Cy7 in a mouse model of ear inflammation. (A) shows probe accumulation in the PMA-treated ear. (B) shows probe specificity shown by pre-injection with a non-fluorescence peptide. Reagent...
Published: 3/8/2012   |   Inventor(s): Dongfeng Pan, Yi Zhang, Li Xiao
Keywords(s):  
Category(s): Recombinant Proteins and Peptides
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