Description:
Reagent Description
This transgenic mouse line expresses the reporter green fluorescent protein (GFP) under the control of the mouse gonadotrophin-releasing hormone (GnRH) promoter. This allows the identification of GnRH neurons in the brain without further processing. Founder strain CBB6/F1 was partially backcrossed onto C57BL6/J so that current mice are approximately 75–80 percent C57BL6/J based on speed congenic analyses. Mice are homozygous for the transgene.
References
Endocrinology. 2000 Jan;141(1):412-9. (Available online.)
J Neurosci. 2010 Oct 6;30(40):13373-83. (Available online.)