Search Results - paul+hoffman

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Novel Compounds for the Treatment of Diarrheal Diseases Executive SummaryUniversity of Virginia researchers have created novel derivative compounds of FDA-approved drug Nitazoxanide (NTZ) that show reduced toxicity, improved bioavailability and greater efficacy against a range of organisms that cause diarrheal diseases. BackgroundDiarrheal diseases are especially common in children, immuno-compromised individuals,... Published: 3/8/2012   |   Inventor(s): Timothy Macdonald, Richard Guerrant, Paul Hoffman, Thomas Ballard Keywords(s): Therapeutics Category(s): Therapeutics

Novel Compounds for Prevention and Treatment of Bacterial Infections and Biofilms Executive SummaryUniversity of Virginia researchers have created novel derivative compounds of FDA-approved drug Nitazoxanide (NTZ) that show reduced toxicity, improved bioavailability and greater efficacy against bacterial infections and biofilms.BackgroundOpportunistic hospital-acquired pathogens, including S. epidermidis and S. aureus, are the leading... Published: 3/8/2012   |   Inventor(s): Timothy Macdonald, Richard Guerrant, Paul Hoffman, Thomas Ballard Keywords(s): Therapeutics Category(s): Therapeutics